Nine experts grapple with the major issues confronting the nation in ensuring continued U.S. leadership in biomedical research and, at the same time, in achieving the fullest possible social benefits from this research. The authors explore the prospects for government support of biomedical research in an era of federal downsizing, the merits of funding disease-based research and untargeted basic research, the promise and challenges of the growing alliance in research between universities and corporations, and the granting of intellectual property rights for publicly funded research.

Claude E. Barfield is a resident scholar at AEI and the director of AEI's science and technology policy studies.

Bruce L. R. Smith, a retired senior staff member at the Brookings Institution, is the author of The Advisers: Scientists in the Policy Process (1992) and American Science Policy since World World II (1990).

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