Debates on scientific issues from genetically modified organisms to climate change have been intense, especially when data are scarce or difficult to interpret. As a society we have trouble resolving these debates in part because the issues are politicized and in part because we lack objective procedures for setting policies based on sound science. Since we can expect many more such controversies in the twenty-first century, it makes sense to consider new mechanisms and institutions that could reduce controversy and lead to more effective policies. At this Joint Center conference, renowned author Michael Crichton will discuss these issues, which are an integral part of his new book, State of Fear.